Gold Nanohelices - Chirality Tomography Markers
The Gold Nanohelices (L,R) are chiral nanoscale markers especially suited for 3D Tomography / Electron Microscopy (EM) / CryoEM. Our chiral markers show pure chirality (L or R), which can easily be detected with EM due to the high contrast and the precise arrangement of the gold nanoparticles.
The Gold Nanohelices (L,R) are fabricated with the DNA origami technique where gold nanoparticles (10nm) are arranged into nanoscale helices (helical pitch 57 nm; length 110 nm; diameter 34 nm).
The markers are shipped ready to use on a TEM grid.
Also available in solution: The Nanohelices are also available in buffer (keep at 4°C): 1x TE (Tris-EDTA-Buffer), 11mM MgCl2. The sample size is ~30µl which is enough for the preparation of more than 10 TEM grids.
DNA-based Self-Assembly of Chiral Plasmonic Nanostructures with Tailored Optical Response. Anton Kuzyk, Robert Schreiber, Zhiyuan Fan, Günther Pardatscher, Eva-Maria Roller, Alexander Högele, Friedrich C. Simmel, Alexander O. Govorov und Tim Liedl. Nature Volume 483 pp311-314 (2012)